If your medical professional agrees you could cease taking fentanyl, they will lessen the strength of your patch gradually. This is very important in case you've been taking it for your long time to lessen the risk of withdrawal symptoms.primidone will lessen the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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Coadministration of pexidartinib (a CYP3A4 inducer) with delicate CYP3A substrates might bring about severe therapeutic failures. If concomitant use is unavoidable, enhance the CYP3A substrate dosage in accordance with authorised products labeling.enzalutamide will minimize the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3